back

Selected Publications

1. Galectin-1 deactivates classically-activated microglia and protects from inflammation-induced neurodegeneration  SC Starossom, ID Mascanfroni, J Imitola, L Cao, K Raddassi, SF Hernandez, R Bassil, DO Croci, JP Cerliani, D Delacour, Y Wang, W Elyaman, SJ Khoury, GA Rabinovich. Immunity (2012) 37:249-263.

2. Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi’s sarcoma. DO Croci , M Salatino, N Rubinstein, JP Cerliani, L Cavallin, HJ Leung, J Ouyang, JM Ilarregui, MA Toscano, C Domaica, MC Croci, E Mesri, A Albini & GA Rabinovich. J Exp Med (2012) In press.

3. Tolerogenic signals delivered by dendritic cells to T cells via a galectin-1-driven immunoregulatory circuit involving IL-27- and IL-10. JM Ilarregui, DO Croci, GA Bianco, M Toscano, M Salatino, M Vermeulen, J Geffner & GA Rabinovich. Nature Immunol (2009) 10: 981–991.

4 Differential glycosylation of Th1, Th2 and Th17 effector cells selectively regulates susceptibility to cell death. MA Toscano, GA Bianco, JM Ilarregui, D Croci, J Correale, J Hernandez, NW Zwirner, F Poirier, E Riley, LG Baum & G Rabinovich. Nature Immunol (2007) 8:825 - 834

5. Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T-cell-mediated rejection: a potential mechanism of tumor-immune privilege. N Rubinstein, M Alvarez, N Zwirner, M Toscano, J Ilarregui, A Bravo, J Mordoh, L Fainboim, O Podhajcer & G Rabinovich. Cancer Cell (2004) 5: 241-251.

6. A pivotal role for galectin-1 in feto-maternal tolerance  SM Blois, JM Ilarregui, M Tometten, M García, A Suphi R Cordo-Russo, M Toscano, G Bianco, B Handjiski, I Tirado, U Markert, F Poirier, J Szekeres-Bartho & P Arck*, G Rabinovich*. Nature Med (2007) 13:1450-1457 (*equal contribution)

7. Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer  GA Rabinovich & DO Croci. Immunity (2012) 36: 322-335.