Henrik Clausen


Selected Publications 


1. Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes.  Wandall HH, Blixt O, Tarp MA, Pedersen JW, Bennett EP, Mandel U, Ragupathi G, Livingston PO, Hollingsworth MA, Taylor-Papadimitriou J, Burchell J, Clausen H. Cancer Res. 70:1306-13 (2010).  


2. O-glycosylation Modulates Proprotein Convertase Activation of Angiopoietin-Like Protein 3 - Possible Role of GALNT2 in Regulation of HDL and TG.  Schjoldager KT, Vester-Christensen MB, Bennett EP, Levery SB, Schwientek T, Yin W, Blixt O, Clausen H   J Biol Chem 285, 36293-36303(2010).

3. A High-throughput O-Glycopeptide Discovery Platform for Seromic Profiling.   Blixt O, Clo E, Nudelman AS, Sørensen KK, Clausen TM, Wandall HH, Livingston P, Clausen H, Jensen KJ   J Proteome Res 9:5250-61 (2010).


4. A systematic study of site-specific GalNAc-Type O-glycosylation modulating proprotein convertase processing.  Schjoldager, K. T-B. G., Vester-Christensen, M. B., Goth, C. K., Petersen, T. N., Brunak, S., Bennett, E. P. Levery, S. B., Clausen, H   J Biol Chem 286:40122-32 (2011).

5. Lectin Domains of Polypeptide GalNAc Transferases Exhibit Glycopeptide Binding Specificity.  Pedersen JW, Bennett EP, Schjoldager KT, Meldal M, Holmér AP, Blixt O, Cló E, Levery SB, Clausen H, Wandall HH  J Biol Chem 286:32684-96 (2011). 


6. Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines.  Steentoft C, Vakhrushev SY, Vester-Christensen MB, Schjoldager KT, Kong Y, Bennett EP, Mandel U, Wandall H, Levery SB, Clausen H   Nat Methods 8:977-82 (2011).  

7. Neurofibromatosis-like phenotype in Drosophila caused by lack of glucosylceramide extension.   Dahlgaard K, Jung A, Qvortrup K, Clausen H, Kjaerulff O, Wandall HH   Proc Natl Acad Sci USA. 109:6987-92 (2012).

8. Engineering mammalian mucin-type O-glycosylation in plants.  Yang Z, Drew DP, Joergensen B, Mandel U, Bach SS, Ulvskov P, Levery SB, Bennett EP, Clausen H, Petersen BL.  J Biol Chem, 287:11911-23 (2012). 


9. The origin and function of platelet glycosyltransferases.   Wandall HH, Rumjantseva V, Sørensen AL, Patel-Hett S, Josefsson EC, Bennett EP, Italiano JE Jr, Clausen H, Hartwig JH, Hoffmeister KM.  Blood 120:626-35(2012).


10. Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells. Schjoldager KT, Vakhrushev SY, Kong Y, Steentoft C, Nudelman AS, Pedersen NB, Wandall HH, Mandel U, Bennett EP, Levery SB, Clausen H.  Proc Natl Acad Sci U S A. 109:9893-8 (2012).